Effect of maternal methyl donor deficient diet on experimental colitis in rat offsprings
نویسندگان
چکیده
منابع مشابه
Methyl deficient diet aggravates experimental colitis in rats
Inflammatory bowel diseases (IBD) result from complex interactions between environmental and genetic factors. Low blood levels of vitamin B12 and folate and genetic variants of related target enzymes are associated with IBD risk, in population studies. To investigate the underlying mechanisms, we evaluated the effects of a methyl-deficient diet (MDD, folate, vitamin B12 and choline) in an exper...
متن کاملMethyl Donor Supplementation Blocks the Adverse Effects of Maternal High Fat Diet on Offspring Physiology
Maternal consumption of a high fat diet during pregnancy increases the offspring risk for obesity. Using a mouse model, we have previously shown that maternal consumption of a high fat (60%) diet leads to global and gene specific decreases in DNA methylation in the brain of the offspring. The present experiments were designed to attempt to reverse this DNA hypomethylation through supplementatio...
متن کاملEffects of Apple (Malus domestica Borkh.) Diet on Rat Reproduction and Sex Ratio of Offsprings
Background & Aims: Apple (Malus domestica Borkh. from Rosaceae family), a rich source of phytoestrogenes has not been thoroughly tested for its reproductive effects. In this study, we investigated the effects of apple diet on rats' reproduction. Method: Nine groups of NMRI rats (n= 10 females + 2 males) with different apple diets (free- apple diet and apple diet in every other day and every tow...
متن کاملthe washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests
در این پایان نامه تاثیر دو نوع تست جزیی نگر و کلی نگر بر به یادسپاری محتوا ارزیابی شده که نتایج نشان دهندهکارایی تستهای کلی نگر بیشتر از سایر آزمونها است
15 صفحه اولMethyl donor supplementation in rats reverses the deleterious effect of maternal separation on depression-like behaviour.
Adverse early life events are associated with altered stress responsiveness and metabolic disturbances in the adult life. Dietary methyl donor supplementation could be able to reverse the negative effects of maternal separation by affecting DNA methylation in the brain. In this study, maternal separation during lactation reduced body weight gain in the female adult offspring without affecting f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2017
ISSN: 2219-2859
DOI: 10.11569/wcjd.v25.i31.2791